| 產(chǎn)品編號 | bs-23740R-BF488 |
| 英文名稱 | Rabbit Anti-Prokineticin 1/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的內(nèi)分泌腺衍生血管內(nèi)皮生長因子抗體 |
| 別 名 | Prokineticin-1/Endocrine-gland-derived vascular endothelial growth factor; Prokineticin1; Prokineticin 1; EG-VEGF; EG VEGF; EGVEGF; PROK1; EGVEGF; PK1; PRK1; PROK1_HUMAN; Black mamba toxin related protein; Endocrine gland derived vascular endothelial growth factor; Endocrine-gland-derived vascular endothelial growth factor; Mambakine; Prokineticin-1. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 心血管 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) 生長因子和激素 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, (predicted: Dog, Cow, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 9.7kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Prokineticin 1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: The protein encoded by this gene induces proliferation, migration, and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. It has little or no effect on a variety of other endothelial and non-endothelial cell types. Its expression is restricted to the steroidogenic glands (ovary, testis, adrenal, and placenta), is induced by hypoxia, and often complementary to the expression of vascular endothelial growth factor (VEGF), suggesting that these molecules function in a coordinated manner. [provided by RefSeq, Sep 2011] Function: Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis. Subcellular Location: Secreted. Tissue Specificity: Localizes to glandular epithelium, stroma and vascular epithelial cells of first trimester decidua (at protein level). Up-regulated in first trimester decidua when compared with non-pregnant endometrium. Expressed in the steroidogenic glands, ovary, testis, adrenal and placenta. Similarity: Belongs to the AVIT (prokineticin) family. Database links: Entrez Gene: 84432 Human Entrez Gene: 246691 Mouse Omim: 606233 Human SwissProt: P58294 Human SwissProt: Q14A28 Mouse Unigene: 514793 Human Unigene: 461353 Mouse Unigene: 82757 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. EG-VEGF是先被發(fā)現(xiàn)的組織特異性促血管生成因子,與多種特定組織腫瘤的發(fā)生及演進相關(guān)，EG-VEGF多在卵巢、睪丸、腎上腺、胎盤等類固醇合成組織中高表達。 |
