| 產(chǎn)品編號 | bsk11056 |
| 英文名稱 | Human IL-18 ELISA Kit |
| 中文名稱 | 白細(xì)胞介素18酶聯(lián)免疫試劑盒 |
| 別 名 | IGIF; interferon gamma-inducing factor IGIF; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; Iboctadekin; IFN gamma inducing factor; IGIF; IL 1 gamma; IL 18; IL 1g; IL1 gamma; IL18 protein; IL1F4; IL1g; IL1gamma; ILIF4; I |
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Specific References (1) | bsk11056 has been referenced in 1 publications.
[IF=3.045] Chongyang Tang. et al. Increased inflammasome-activated pyroptosis mediated by caspase-1 in Rasmussen’s encephalitis. Epilepsy Res. 2021 Dec;:106843 ELISA ; Human.
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| 種 屬 | Human |
| 線性范圍 | 39 - 2500 pg/mL |
| 應(yīng)用范圍 | S/P/CC |
| 檢測限 | 20 pg/mL |
| 適用樣品基質(zhì) | cell culture supernates, serum, and plasma. |
| 保存條件 | Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.). |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
IL18 (IFN-gamma-inducing factor, IGIF) is a novel pro-inflammatory cytokine that augments natural killer (NK) activity in spleen cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity.IL18 also has other biological properties such as stimulation of Fas ligand expression, and induction of CC and CXC chemokines. IL18 increases production of competent HIV. IL18 is related to the IL1 family. One of the IL18 receptor chains is the IL1 receptor-related protein, a member of the IL 1R family. Like IL1 , IL18 is first synthesized as a leaderless precursor requiring the IL1 converting enzyme (ICE) for cleavage into an active molecule. IL18 may play a role in tissue injury in inflammatory reactions.
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