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Plakophilin 3 Rabbit pAb (bs-12703R)  
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50ul/1180.00元
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產(chǎn)品編號(hào) bs-12703R
英文名稱 Plakophilin 3 Rabbit pAb
中文名稱 橋粒斑菲素蛋白3抗體
別    名 PKP 3; PKP3; PKP3_HUMAN; Plakophilin 3b; Plakophilin-3; Plakophilin3.  
研究領(lǐng)域 細(xì)胞生物  發(fā)育生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Dog)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 87 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Plakophilin 3: 631-730/797 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]

Function:
May play a role in junctional plaques.

Subcellular Location:
Nucleus. Cell junction > desmosome. Nuclear and associated with desmosomes.

Tissue Specificity:
Found in desmosomes of most simple and stratified epithelia. Not found in foreskin fibroblasts and various sarcoma-derived cell lines. Beside dendritic reticular cells of lymphatic follicles not found in non-epithelial desmosome-bearing tissues.

Similarity:
Belongs to the beta-catenin family.
Contains 8 ARM repeats.

SWISS:
Q9Y446

Gene ID:
11187

Database links:

Entrez Gene: 11187 Human

Entrez Gene: 56460 Mouse

Entrez Gene: 293619 Rat

Omim: 605561 Human

SwissProt: Q9Y446 Human

SwissProt: Q9QY23 Mouse

Unigene: 534395 Human

Unigene: 350037 Mouse

Unigene: 144803 Rat



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