| 產(chǎn)品編號(hào) | bs-5439R |
| 英文名稱(chēng) | phospho-MAP4 (Ser1046) Rabbit pAb |
| 中文名稱(chēng) | 磷酸化微管相關(guān)蛋白4抗體 |
| 別 名 | MAP4(phospho Ser1046); MAP4(phospho S1046); DKFZp779A1753; MAP-4; MAP4; MAP4_MOUSE; MGC8617; Microtubule associated protein 4; Microtubule-associated protein 4; OTTHUMP00000210723; OTTHUMP00000210725; OTTHUMP00000210727; OTTHUMP00000210730. |
| 產(chǎn)品類(lèi)型 | 磷酸化抗體 |
| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞周期蛋白 細(xì)胞骨架 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat,Rabbit,Pig,Cow,Chicken,Dog) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 117 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthesised phosphopeptide derived from mouse MAP4 around the phosphorylation site of Ser1046: VG(p-S)LD |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The MAP4 (Microtubule associated protein 4)is a non neuronal microtubule associated protein. It promotes microtubule assembly.The phosphorylation of the Pro rich region in the C-terminus negatively regulates MAP4 activity to promote microtubule assembly. Function: Non-neuronal microtubule-associated protein. Promotes microtubule assembly. Subunit: Interacts with SEPT2; this interaction impedes tubulin-binding (By similarity). Subcellular Location: Cytoplasm, cytoskeleton. Tissue Specificity: Testis, striated and cardiac muscle. Post-translational modifications: Phosphorylated at serine residues in K-X-G-S motifs by MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), causing detachment from microtubules, and their disassembly (By similarity). Phosphorylation on Ser-760 negatively regulates MAP4 activity to promote microtubule assembly. Isoform 4 is phosphorylated on Ser-333 and Ser-334 (By similarity). Similarity: Contains 4 Tau/MAP repeats. SWISS: P27546 Gene ID: 17758 Database links: Entrez Gene: 4134 Human Entrez Gene: 17758 Mouse Omim: 157132 Human SwissProt: P27816 Human SwissProt: P27546 Mouse Unigene: 517949 Human Unigene: 217318 Mouse Unigene: 443428 Mouse Unigene: 484451 Mouse Unigene: 203122 Rat |
| 產(chǎn)品圖片 |
Sample:
A673(Human) Cell Lysate at 30 ug
Primary: Anti- phospho-MAP4 (Ser1046) (bs-5439R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 117 kD
Observed band size: 117 kD
|
