| 產(chǎn)品編號 | bs-2521R |
| 英文名稱 | CD94 Rabbit pAb |
| 中文名稱 | NK細(xì)胞表面抑制性受體CD94抗體 |
| 別 名 | Killer cell lectin-like receptor subfamily D member 1; CD 94; CD94 antigen; KLRD 1; KLRD1; KLRD1 protein; KP 43; KP43; Natural killer cells antigen CD94; NK cell receptor; Killer cell lectin-like receptor subfamily D member 1; KLRD1_HUMAN. |
| 研究領(lǐng)域 | 免疫學(xué) 細(xì)胞膜受體 細(xì)胞類型標(biāo)志物 自然殺傷細(xì)胞 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Mouse,Rat) |
| 產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 20 kDa |
| 檢測分子量 | 25-30 |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CD94: 71-179/179 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq] Function: Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Subunit: Can form disulfide-bonded heterodimer with NKG2 family members. Subcellular Location: Membrane; Single-pass type II membrane protein. Tissue Specificity: Natural killer cells. Similarity: Contains 1 C-type lectin domain. SWISS: Q13241 Gene ID: 3824 Database links: Entrez Gene: 3824 Human Omim: 602894 Human SwissProt: Q13241 Human Unigene: 524251 Human Unigene: 562457 Human |
