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Stra8 Rabbit pAb (bs-1903R)  
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產(chǎn)品編號(hào) bs-1903R
英文名稱(chēng) Stra8 Rabbit pAb
中文名稱(chēng) 視黃酸激活基因8抗體
別    名 Stimulated by retinoic acid Gene 8; STRA8_HUMAN; Stimulated by retinoic acid gene 8 protein homolog; STRA 8; STRA8.  
Specific References  (5)     |     bs-1903R has been referenced in 5 publications.
[IF=6.582] Changliang Hou. et al. Stella Regulates the Development of Female Germline Stem Cells by Modulating Chromatin Structure and DNA Methylation. INT J BIOL SCI. 2022; 18(7): 3006–3018  WB ;  Mouse.  
[IF=5.048] Yuling Tang. et al. Transcriptomic Profiling of Mouse Mast Cells upon Pathogenic Avian H5N1 and Pandemic H1N1 Influenza a Virus Infection. Viruses-Basel. 2022 Feb;14(2):292  WB ;  Mouse.  
[IF=4.221] Jinxia Zhai. et al. BDE-209 induce spermatocytes arrest at early-pachytene stage during meiotic prophase I in mice. Toxicology. 2022 Feb;467:153061  WB,IF ;  Mouse.  
[IF=2.959] Zhuang M et al. Reelin regulates male mouse reproductive capacity via the sertoli cells.(2018) J. Cell. Biochem. 2018 Oct 18  WB ;  Mouse.  
[IF=0] Wenhuan Chai. et al. Visualizing Cathepsin K-Cre Expression at the Single-Cell Level with GFP Reporters. JBMR Plus. 2022 Dec;:e10706  IF ;  Mouse.  
研究領(lǐng)域 細(xì)胞生物  發(fā)育生物學(xué)  細(xì)胞凋亡  細(xì)胞周期蛋白  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Mouse,Rat (predicted: Human)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 45 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Stra8: 201-300/330 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a retinoic acid-responsive protein. A homologous protein in mouse has been shown to be involved in the regulation of meiotic initiation in both spermatogenesis and oogenesis, though feature differences between the mouse and human proteins suggest that these homologs are not entirely functionally equivalent. It is thought that this gene may play a role in spermatogenesis in humans. [provided by RefSeq, Nov 2010]

Function:
Required for the transition into meiosis for both female and male germ cells. In female germ cells, required for premeiotic DNA replication and subsequent events in meiotic prophase

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Expressed specifically in testis.

Post-translational modifications:
Phosphorylated.

SWISS:
Q7Z7C7

Gene ID:
346673

Database links:

Entrez Gene: 346673 Human

Entrez Gene: 20899 Mouse

Entrez Gene: 500079 Rat

Omim: 609987 Human

SwissProt: Q7Z7C7 Human

SwissProt: P70278 Mouse

Unigene: 592279 Human



Stra8是哺乳動(dòng)物生殖細(xì)胞由有絲分裂轉(zhuǎn)變?yōu)闇p數(shù)分裂前特異表達(dá)的基因,是一種生殖細(xì)胞特異性表達(dá)并受視黃酸誘導(dǎo)的基因。Stra8是減數(shù)分裂起始的調(diào)節(jié)蛋白,參與了雌性胚胎期和雄性出生后生殖細(xì)胞的減數(shù)分裂起始過(guò)程。
產(chǎn)品圖片
Sample: Testis (Rat) Lysate at 40 ug Primary: Anti-bs-1903R (bs-1903R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 45 kD Observed band size: 45 kD
Sample: Testis (Mouse) Lysate at 40 ug Primary: Anti-bs-1903R (bs-1903R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 45 kD Observed band size: 45 kD
Paraformaldehyde-fixed, paraffin embedded (Rat testis); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Ant
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